Profhilo STRUCTURA
volume restoration for the mid and lower face
Profhilo Structura® is a regenerative injectable treatment which is hyaluronic acid-based and designed to restore the facial fat beneath the skin: the adipose tissue that gives a younger face much of its softness, contour and support. It is used mainly through the mid and lower face, where age-related changes in this fat can leave the contours flatter, softer or less defined.
At Clinic Dr Paris, treatment is led by Dr Paris Acharya, aesthetics expert and former maxillofacial surgeon. Dr Paris assesses the architecture of your face, reviewing how the fat and supporting tissues have changed, to determine how Structura® (or other options) would best restore support while preserving your natural features.
Key Details
DURATION: Allow 30 to 45 minutes
NO. REQUIRED: 2 (1 month apart)
RESULTS: Develop over several weeks; optimal at around 2 to 3 months
DOWNTIME: Minimal; any small bumps or swelling usually settle within a few to 24 hours
COMFORT: 4/5
PRICE: From £650
Key Benefits
Restores lost facial volume
Lifts & supports facial contours
Regenerates facial fat pads
Firms & hydrates underlying tissue
Supports collagen & skin quality
TREATMENT INFORMATION
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Your patient journey starts with a chat by phone or email to discuss what you're hoping to treat. We can also arrange a virtual consultation with Dr Paris (or Dr Alexa) if you'd like to ask questions before deciding whether to book.
We then arrange an in-depth, in-person consultation, where Dr Paris or Dr Alexa assesses your facial structure and any relevant medical background, and takes the time to understand the results you're looking to achieve, before advising the treatment choice(s) best suited to you.
You'll have plenty of time to ask questions and, particularly if you're new to injectables, we'll make sure you are fully informed and comfortable. There is never any pressure to have treatment. If you wish to go ahead, you may do so at the same appointment, if appropriate, or book another date, as suits you.
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Profhilo Structura is suited to those noticing:
early to moderate age-related changes in facial firmness, definition or support
softening of the contours across the cheeks and mid-face
or a gentle heaviness developing around the jawline
It suits those who would like subtle, natural support rather than the fuller look of a dermal filler.
Significant or rapid weight loss - including that associated with GLP-1 medications - often leaves the face looking hollowed and fatigued. While this is driven by depleted facial fat pads, it is also caused by a sudden loss of skin elasticity and support. As each face undergoes a unique structural shift during weight loss, our doctors would always assess you individually to determine the optimal treatment choice(s) for structural tissue regeneration and surface skin remodelling.
Structura's sister product, Profhilo®, is more suitable if your main concern is surface hydration, radiance or fine lines. Where significant volume replacement is needed, a different approach may be called for. Dr Paris will advise on the most appropriate option for your specific face at consultation.
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Injectable treatments - such as Profhilo Structura - are carried out by Dr Paris Acharya and Dr Alexa Croffey at Clinic Dr Paris.
Dr Paris Acharya BDS Hons MBChB MFDS MRCS Ed, an aesthetic doctor, former maxillofacial surgeon and a recognised authority in regenerative aesthetic medicine.
Her background in medicine, dentistry and maxillofacial surgery gives her an in-depth understanding of facial anatomy, including the fat compartments Profhilo Structura works within. Her approach is measured and considered: to restore support and definition while preserving your own unique features.
View Dr Paris’ bio and Dr Alexa’s bio.
Do get in touch if you have any questions as we appreciate the importance of finding the right practitioner for you.
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Profhilo Structura is formulated with hyaluronic acid, the molecule which occurs naturally in the skin and tissues and binds water to keep them hydrated and supported. It depletes over time with age.
Facial fat, or adipose tissue, sits in distinct compartments (pockets of fat) beneath the skin that give the face its shape and support. With age, these can lose volume and quality, and shift position, softening the contours and definition many people notice over time.
Where a dermal filler is placed to add volume or shape in a specific area, Structura is delivered into the superficial fat itself. It is administered through a fine cannula, usually via a single entry point on each side of the face, allowing precise placement and, for many people, less bruising than multiple needle injections.
Within the fat, it is designed to support the tissue and prompt it to firm and regenerate, helping restore the structure and definition the face loses over time.
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Numbing cream is applied beforehand to ensure the treatment is comfortable, and most people tolerate it very well.
Structura treatment is generally gentle as it is delivered through a fine cannula and a single entry point on each side (rather than the multiple needle points used for standard Profhilo).
Downtime is normally minimal. Any small bumps or swelling at the injection points tend to settle within a few hours to 24 hours (typically milder and faster than with standard Profhilo).
You may also notice mild redness, and, as with any injectable, there is a small chance of bruising within 48 hours of treatment.
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Profhilo Structura works gradually meaning you'll usually begin to notice an improvement in support and contour over the weeks following treatment, as the tissue remodels.
Optimal results are usually seen around 2 to 3 months, and continue to build after your second session. Individual responses vary.
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The usual course is 2 treatments, around a month apart, though some people benefit from a third, depending on your treatment response and desired results.
Results typically last around 6 to 12 months. We usually recommend a maintenance treatment every 6 to 9 months, guided by how you respond.
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We recommend that you have Profhilo Structura at least 2 weeks before any important social or work events, and you'll have the second treatment around a month after the first, so we book your appointments accordingly.
To reduce the risk of bruising, we advise you to avoid:
Alcohol for 24 hours beforehand
Aspirin, ibuprofen and omega-3 supplements for 2 days before
After treatment, we advise you to:
Not apply makeup for 30 minutes
Avoid travelling for 24 hours
Avoid strenuous exercise, saunas and heat for 24 to 48 hours
Avoid pressing or massaging the treated area for 48 hours, so the product settles evenly
frequently asked questions
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Profhilo Structura is an injectable hyaluronic acid treatment, part of the Profhilo family, developed specifically to work in the layer of fat beneath the skin that gives the face its shape and support.
Structura is designed to support and regenerate this facial fat where age-related changes have softened the contours, helping restore firmness, definition and structure across the mid and lower face, for a subtle, natural result rather than an added or filled appearance. This sets it apart from a dermal filler: fillers use a firmer, cross-linked gel to restore volume and define contours directly, whereas Structura works with the facial fat itself, supporting and remodelling it.
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Profhilo and Profhilo Structura do different jobs and can be used together, if appropriate.
Profhilo works in the skin itself, almost like an injectable moisturiser: a fluid hyaluronic acid that deeply hydrates and stimulates collagen to improve radiance, elasticity and fine, crepey texture.
Profhilo Structura is a firmer formulation that works deeper, within the fat compartments beneath the skin, to support and regenerate the facial fat where midface flattening or a softening jawline have begun to show. In short, Profhilo refines the quality of the skin; Structura restores structure and support.
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Profhilo Structura is used mainly through the mid and lower face, where age-related changes in the facial fat most affect firmness, definition and support. This typically includes the cheeks and mid-face, and the jawline. Your doctor will advise the appropriate treatment areas for you at consultation.
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It can help where mild to moderate sagging around the jawline or lower face is driven by changes in the deeper facial fat, supporting and firming that tissue for a more defined contour. Profhilo Structura isn't a facelift and won't correct significant skin laxity. Dr Paris will advise whether treatment will give optimal results for your specific concerns around skin laxity, or suggest other options if more suitable.
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Dermal fillers are generally made from a firmer, more structured hyaluronic acid gel, one in which the molecules are bonded together (or "cross-linked") to hold their shape, and are used to restore volume, define contours and provide structural support where needed. Profhilo Structura works differently: rather than placing a shaping gel, it's designed to support and regenerate the facial fat itself, improving structure and definition from within, for natural support rather than an obviously filled look.
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No. Structura is designed to restore your own facial structure and support, not to result in an obviously fuller or differently shaped appearance. The aim is a subtle, natural result that works with your existing features and preserves your natural proportions.
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Yes, where appropriate. Structura can form part of a wider plan alongside Profhilo and other skin-quality or regenerative treatments. Dr Paris will advise on the right combination and timing at your consultation.
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Profhilo Structura is a hyaluronic acid treatment with a well-established safety profile; in the published clinical studies, no serious adverse events beyond bruising were recorded. It is carried out by Dr Paris following a full assessment of your medical history and suitability. Side effects are usually mild and temporary, such as redness, swelling or small bumps at the injection points, and Dr Paris will discuss any risks fully with you.
Why CHoose clinic dr paris?
Clinic Dr Paris is a unique sanctuary that blends the principles of transformative medical aesthetics, longevity medicine and wellbeing. Founded by renowned expert, Dr Paris Acharya, Clinic Dr Paris has a passion and commitment to clinical excellence and offers an uplifting, personalised journey to realising your full potential - from the inside out.
Meet the Founder
Dr Paris Acharya
(BDS Hons MBChB MFDS MRCS ED)
Dr. Parisha (Paris) Acharya, founder of Clinic Dr Paris, is a leading expert in London’s aesthetics, injectables, and hormone replacement therapy.
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With a background in maxillofacial surgery and medicine, she blends artistic vision with clinical expertise to deliver natural, elegant results. Her holistic approach ensures personalised treatments that enhance both skin health and overall wellbeing. A mentor at Ardour Academy and a trusted voice in aesthetics, Dr. Paris is dedicated to patient care, education, and innovation. Choosing her expertise means embracing a balanced, radiant approach to beauty and wellness, tailored to your unique needs and aspirations.
Where is clinic dr paris?
Clinic Dr Paris is discretely located yet in a prime position in central London, adjacent to both Marylebone High Street’s boutiques & restaurants and to the Harley Street health district. The clinic is easily accessible by taxi, car or tube (8 minute’ walk from Baker Street or Regent’s Park stations; 15 minute walk from Marylebone & Oxford Circus underground stations).
Address:
1st Floor, Elliott House
28A Devonshire Street
London
W1G 6PS
TO BOOK OR LEARN MORE
Whether you’re exploring treatment options, have questions or would like to book a consultation with Dr Paris in clinic or by video, please get in touch.
We’d love to hear from you.